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Tablets are solid dosage forms usually containing active pharmaceutical ingredient and excipients in powder, crystalline or granular form with or without diluents which is prepared either by moulding or compression process. They are solid, biconvex or flat in shape and vary in size, shape and weight which is depends on the medicaments which are used for preparation. They are also varying in hardness, disintegration; dissolution characteristics and thickness depend on their intended use and method of manufacture. Tablets are the most widely used solid dosage forms because of ... Read More
(1) when the machine works normally for a long time, the parts that are in direct contact with the drug should be cleaned regularly. When the drug batch is changed or the time of withdrawal is long, the parts should be cleaned regularly. (2) the transmission mechanism under the working table of the machine should often add appropriate amount of lubricating oil (grease), in order to reduce the wear of moving parts. (3) the filling machine runs 250-300h to replace the lubricating oil in the main drive drop box. Check the reducer of powder feeding mechanism and replenish lubri ... Read More
10 Easy Steps for Cleaning Your Tablet Press Nothing can slow production down like equipment that malfunctions or stops working altogether. Performing regular, preventative maintenance of equipment is essential and helps keep pharmaceutical tablet presses functioning efficiently and smoothly. Tablet presses that are not well maintained can cause a multitude of problems, creating defective products that are mal-formed, contaminated or contain improper dosages. One of the most important steps to maintaining your tablet press is keeping it clean. It’s also important to have sy ... Read More
Tablet presses require regular inspection and maintenance to prevent premature wear and tableting problems. Preventive maintenance (PM) is something that pharmaceutical manufacturers should employ on a regular basis, though it remains somewhat alarming to see how many wait until they experience an “uh-oh” moment before acting. Tablet-press manufacturers can offer varying guideposts for the timing of such PM intervals, but there are some easy signals to remain cognizant of that should prompt proactive behavior. A few of these include odd noises, erratic tablet weights, and p ... Read More
Poor tooling condition can cause many tableting problems, but these problems can be minimized or eliminated by adopting a simple, seven-step tool-care process. We can adopt a seven-step process resolves tableting problems, which is a logical, planned, and professional approach to tooling maintenance and storage. The seven steps are summarized as follows: ◆ Clean: The compressing chamber should timely clearance. Rotary tablet press after working hours, tableting interior will be full of fine powder of materials, the powder adheres to these tiny punch, punch hole and the hole ... Read More
There are nine types of machine maintenance. Each one has its pros and cons (except reactive maintenance, which is all cons), and can be mixed and matched with assets to create a balanced maintenance program. Reactive maintenance Reactive maintenance refers to repairs done when a machine has already reached failure. Since it’s unexpected, unplanned, and usually leads to rushed, emergency repairs, It’s often called “fighting fires.” Run to fail maintenance Run to fail maintenance is very similar to reactive maintenance. It involves letting a piece of equipment run until it b ... Read More
Waiting until tablet presses or other pieces of pharmaceutical equipment break down can be a costly mistake. Instead of waiting for malfunctions or unexpected incidents that may halt or decrease production, manufacturing facility managers should implement consistent preventative maintenance procedures. Daily inspections and regular tune-ups can maintain tablet presses in like-new condition and reduce irregular contact wear, noises, and process malfunctions. Regular preventative maintenance also ensures that tablets are produced according to exact physical and chemical param ... Read More
Imagine waiting at the pharmacist’s as your prescription gets filled up. The guy filling your prescription smiles as he counts… One, two, three, four, five… while at the same time trying to maintain eye contact with you. He drops each successive pill inside a small package where he writes ‘3 times a day for 10 days’ on the label. You don’t have to be a mathematical genius to know that 3 times 10 totals to 30 tablets, right? But what if, when you arrive home and on a whim decide to count the drugs, and discover instead of 30 you have 50 tablets? If it were a bag of apples an ... Read More
Labeling machine is one of the packaging equipment which put rolls of self-adhesive paper tags mounted on PCB, products and bags. Labeler is an indispensable part of modern packaging machines. Currently in China, types of labeling machines are gradually increasing, as well as technological level, which means changing from manual or semi-automatic technology to fully-automatic technology. With more attention on it, maintenance on labeler is necessary and can prolong its life. Following are 4 aspects to maintain labeling machines. 1.Installing and operating environment: it sh ... Read More
The beginning of the work process is that the bottle is fed to the labelling machine at a constant speed on the conveyor. The mechanical fixture separates the bottles a fixed distance and pushes the bottle in the direction of the conveyor. The mechanical system of the labeler includes a drive wheel, a labeling wheel, and a reel. The drive wheel intermittently drags the label belt to move, the label tape is pulled out of the spool, and the label wheel is pressed against the bottle by the labeling wheel. An open-loop displacement control is used on the reel to maintain the te ... Read More