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Troubleshoot granulation binder spray problems by checking nozzle clogging, spray deflection, droplet size, binder flow, and nozzle position. ... Read More
Learn how to diagnose blister pocket depth variation by checking heat, forming pressure, venting, web tension, material lots, and wall-thickness data. ... Read More
Learn how to diagnose capsule fill weight variation by checking powder flow, density, moisture, machine speed, and dosing system settings. ... Read More
Learn desiccant inserter troubleshooting methods to identify sensor, static, and timing issues causing desiccant sachet insertion failures. ... Read More
Diagnose rising tablet ejection force by checking lubrication, die-wall condition, take-off alignment, tooling, and speed in a controlled sequence. ... Read More
Key Takeaway Capsule fill weight variation is rarely solved reliably by changing one machine setting at random. First confirm that the variation is real and separate shell-weight variation from net fill-weight variation; then check powder flow, bulk-density changes, moisture, powder-bed consistency, machine speed, and the dosing mechanism in a controlled sequence. The most useful evidence is a time-ordered weight record linked to material properties and actual machine settings. Change only one factor at a time under an approved procedure so that an apparent improvement can ... Read More
Effective tablet defects troubleshooting requires separating the visible symptom from its possible causes. Sticking and picking usually involve adhesion at the punch face, while capping and lamination indicate that the compact cannot retain its structure during decompression or ejection. Key Principle: Start with defect location, granule condition, tooling inspection, and batch records. Then change only one formulation, compression, or machine parameter at a time under an approved SOP or investigation protocol. What Are Sticking, Picking, Capping, and Lamination? Sticking, ... Read More
Consistent powder quality is critical for producing safe and effective tablets and capsules. Before a formulation reaches tablet compression or capsule filling, its active pharmaceutical ingredient (API) and excipients must be distributed as uniformly as possible. An uneven blend can lead to API content variation, inconsistent tablet weight, poor capsule filling, process interruptions, and rejected batches. For low-dose products, even a small mixing or segregation problem can have a significant effect on finished-dose accuracy. A V Blender is widely used because its gentle ... Read More
Exhibition Announcement SED Pharma to Present Pharmaceutical Machinery Solutions at Dubai Pharma Exhibition 2026 Meet the SED Pharma team and discover advanced pharmaceutical machinery solutions at one of the industry's most anticipated events. 📅 Date Aug 25–27, 2026 📍 Venue Dubai World Trade Centre 🏷️ Booth 2F26 🌍 Location Dubai, UAE About SED Pharma With extensive experience in pharmaceutical equipment manufacturing, SED Pharma provides advanced machinery and integrated solutions for pharmaceutical production and packaging processes. The company is committed to helping gl ... Read More
Introduction In pharmaceutical manufacturing, production efficiency plays a critical role in maintaining competitiveness, controlling operating costs, and meeting increasing market demand. As a core piece of tablet production equipment, a tablet press machine directly influences output capacity, tablet consistency, and overall manufacturing performance. However, improving tablet press efficiency requires more than simply increasing machine speed. Production performance depends on how well equipment settings, materials, workflows, and process control work together. By improv ... Read More